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ACE-031
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Peptide
Myostatin Inhibitor
ACE-031
Overview
Summary
Clinical-grade myostatin pathway inhibitor — terminated in muscle dystrophy trials.
Category
Myostatin Inhibitor
Mechanism
Soluble activin receptor type IIB decoy — sponges up myostatin.
Effects
Top outcomes
  • Lean muscle72
Evidence
Emerging
Practical
Half-life
~10-15 days
Administration
subq
Risk
Legal status
research only
Safety
Vascular side effects (nosebleeds, gum bleeding) led to trial halts.
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