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Attribute
Metabolic
AICAR
SummaryOriginal 'exercise-mimetic' research compound. WADA-prohibited in sport.
MechanismAdenosine analog that activates AMPK, mimicking the metabolic state of exercise. Increases fatty-acid oxidation and glucose uptake in skeletal muscle.
Top outcomes
  • Fat loss60
  • Energy55
Evidenceemerging
Half-lifeShort (~minutes parent compound)
Administrationsubq, iv
Legal statusresearch only
SafetyTransient hyperuricemia and lactic acidosis reported at high IV doses. Limited chronic-use data.
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