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ARA-290
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Peptide
Neuroprotective
ARA-290
Overview
Summary
EPO-derived peptide for small-fiber neuropathy and inflammatory nerve pain.
Category
Neuroprotective
Mechanism
11-amino-acid peptide derived from erythropoietin. Activates the innate-repair receptor (IRR) without erythropoietic effects — anti-inflammatory and neuroprotective.
Effects
Top outcomes
  • Inflammation75
  • Recovery60
Evidence
Emerging
Practical
Half-life
~2 minutes (active signaling persists longer)
Administration
subq
Risk
Legal status
research only
Safety
Well tolerated in trials, including no measurable change to hematocrit at therapeutic doses.
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