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Tesofensine
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Peptide
Monoamine Reuptake Inhibitor
TesofensineOverview
Summary
Non-peptide oral weight-loss agent with strong Phase 2 data.
Category
Monoamine Reuptake Inhibitor
Mechanism
Triple reuptake inhibitor of noradrenaline, dopamine and serotonin.
Effects
Top outcomes
- Fat loss80
- Energy60
Evidence
Emerging
Practical
Half-life
~9 days
Administration
oral
Risk
Legal status
research only
Safety
Blood pressure and heart rate increases; insomnia; mood effects.
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