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| Attribute | Growth Hormone Secretagogue Ipamorelin | Growth Hormone Releasing Hormone Analog CJC-1295 (no DAC) | Growth Hormone Secretagogue Hexarelin |
|---|---|---|---|
| Summary | Clean GH pulse — widely used for sleep, recovery, and lean composition. | GHRH partner to Ipamorelin — together they amplify the GH pulse. | Strongest GH-releasing peptide in the GHRP family. |
| Mechanism | Selective ghrelin receptor agonist that triggers a clean, pulsatile GH release without strongly affecting cortisol or prolactin. | A GHRH analog that extends the duration of GH release. The no-DAC variant is short-acting and pulse-friendly. | Potent GHRP. Strong GH release with possible cardioprotective effects. |
| Top outcomes |
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| Evidence | emerging | emerging | emerging |
| Half-life | ~2 hours | ~30 min (no DAC) | ~1 hour |
| Administration | subq | subq | subq |
| Legal status | research only | research only | research only |
| Safety | Generally well tolerated; mild head-rush or hunger reported by some users. | Well tolerated when used physiologically. | Desensitization with prolonged use; cycle dosing recommended. |