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Ipamorelin

Also: Ipa

Clean GH pulse — widely used for sleep, recovery, and lean composition.

Evidence
emerging
Legal status
research only
Half-life
~2 hours
Routes
subq
What it is

Ipamorelin is prized for being one of the cleanest growth-hormone secretagogues, with minimal effect on cortisol, prolactin, or appetite. It produces a short, sharp GH pulse — most commonly dosed before sleep to amplify the natural nighttime release.

Mechanism

Selective ghrelin receptor agonist that triggers a clean, pulsatile GH release without strongly affecting cortisol or prolactin.

Outcomes it's matched to
Safety

Generally well tolerated; mild head-rush or hunger reported by some users.

  • Active cancer
  • Pregnancy
Legal context

Not FDA-approved. Research-use only in the US.

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