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Attribute
Longevity
NAD+
SummaryCofactor for mitochondrial energy and sirtuin-mediated longevity pathways.
MechanismCoenzyme essential for cellular energy production and sirtuin activity. Direct infusion or injection raises tissue levels.
Top outcomes
  • Energy78
  • Longevity72
  • Cognition55
Evidenceemerging
Half-lifeVaries by route
Administrationsubq, im
Legal statusapproved some regions
SafetyInjection can be uncomfortable (flushing, pressure). IV is well tolerated when titrated.
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