NAD+
Also: Nicotinamide Adenine Dinucleotide
Cofactor for mitochondrial energy and sirtuin-mediated longevity pathways.
Evidence
emerging
Legal status
approved some regions
Half-life
Varies by route
Routes
subq · im
What it is
NAD+ levels decline with age. Direct injection or IV infusion is used to raise tissue NAD+, supporting energy production and DNA repair pathways. Oral precursors (NR, NMN) are more common but less direct.
Mechanism
Coenzyme essential for cellular energy production and sirtuin activity. Direct infusion or injection raises tissue levels.
Outcomes it's matched to
- STRENGTH78%
- STRENGTH72%
- STRENGTH55%
Safety
Injection can be uncomfortable (flushing, pressure). IV is well tolerated when titrated.
- Active malignancy (theoretical)
Legal context
Available via specialty pharmacies and IV clinics.