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PT-141
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Peptide
Melanocortin Agonist
PT-141
Overview
Summary
Centrally-acting libido peptide — FDA-approved for premenopausal HSDD.
Category
Melanocortin Agonist
Mechanism
MC4R agonist that acts centrally on sexual desire pathways, independently of vascular flow.
Effects
Top outcomes
  • Libido90
Evidence
Established
Practical
Half-life
~2 hours
Administration
subqnasal
Risk
Legal status
rx only
Safety
Nausea, flushing, and transient blood-pressure increase reported.
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