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Semaglutide
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Peptide
GLP-1 Agonist
SemaglutideOverview
Summary
The category-defining GLP-1 for weight loss and metabolic health.
Category
GLP-1 Agonist
Mechanism
Long-acting GLP-1 receptor agonist. Slows gastric emptying, suppresses appetite, and improves glycemic control.
Effects
Top outcomes
- Fat loss94
- Inflammation50
Evidence
Established
Practical
Half-life
~7 days
Administration
subqoral
Risk
Legal status
rx only
Safety
GI side effects (nausea, constipation) common. Lean-mass loss possible without resistance training.
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