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| Attribute | Nootropic Semax | Nootropic Selank |
|---|---|---|
| Summary | Russian nootropic for focus and neuroprotection. | Russian anxiolytic nootropic — calm focus without sedation. |
| Mechanism | ACTH(4-10) analog. Upregulates BDNF and modulates dopamine. | Synthetic analog of tuftsin. Modulates GABA, serotonin, and BDNF pathways. |
| Top outcomes |
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| Evidence | emerging | emerging |
| Half-life | Short (nasal action) | Short (nasal action) |
| Administration | nasal | nasal |
| Legal status | research only | research only |
| Safety | Well tolerated; rare mild nasal irritation. | Very well tolerated in available studies. |