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| Attribute | Cosmetic peptide (topical) SNAP-8 |
|---|---|
| Summary | Topical 'Botox-mimetic' peptide for expression-line softening. |
| Mechanism | Eight-amino-acid peptide that competes with the SNAP-25 protein in the SNARE complex, limiting neurotransmitter release at the neuromuscular junction in expression-line areas. |
| Top outcomes |
|
| Evidence | emerging |
| Half-life | N/A (topical, repeated application) |
| Administration | topical |
| Legal status | approved some regions |
| Safety | Excellent topical safety. Effect is modest and requires consistent multi-week application. |