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| Attribute | Healing & Repair BPC-157 | Healing & Repair TB-500 | Skin & Regeneration GHK-Cu |
|---|---|---|---|
| Summary | The flagship healing peptide. Used to accelerate tendon, ligament, and gut repair. | Soft-tissue healing peptide — frequently stacked with BPC-157. | The original copper peptide — collagen, skin tone, hair density. |
| Mechanism | A pentadecapeptide fragment of a gastric protein. Promotes angiogenesis, upregulates growth factors, and stabilizes the gut barrier. | Synthetic fragment of Thymosin Beta-4. Upregulates actin, supports cell migration and new blood-vessel formation. | Copper-binding tripeptide. Stimulates collagen, elastin, and antioxidant gene expression; supports wound healing. |
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| Evidence | emerging | emerging | emerging |
| Half-life | ~4 hours (injectable) | ~2-3 hours | Short systemically; topical action is local |
| Administration | subq, oral | subq, im | topical, subq |
| Legal status | research only | research only | approved some regions |
| Safety | Well tolerated in available studies. Long-term human safety data is limited. | Limited human safety data; well tolerated anecdotally. | Very well tolerated topically. Mild local reaction possible with injection. |