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EpitalonMOTS-cThymosin Alpha-1NAD+
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Overview
Summary
Pineal-derived longevity peptide with proposed telomerase effects.
Mitochondrial peptide for metabolic flexibility and exercise capacity.
Immune modulator — used clinically for chronic viral infections and immune support.
Cofactor for mitochondrial energy and sirtuin-mediated longevity pathways.
Category
Longevity
Mitochondrial
Immune Modulation
Longevity
Mechanism
Tetrapeptide derived from pineal extract. Proposed to upregulate telomerase activity.
Mitochondrial-derived peptide. Activates AMPK, improves insulin sensitivity and mitochondrial function.
28-amino-acid peptide that modulates T-cell maturation and immune balance.
Coenzyme essential for cellular energy production and sirtuin activity. Direct infusion or injection raises tissue levels.
Effects
Top outcomes
- Longevity78
- Sleep55
- Energy80
- Longevity70
- Fat loss60
- Inflammation70
- Recovery60
- Longevity55
- Energy78
- Longevity72
- Cognition55
Evidence
Anecdotal
Emerging
Established
Emerging
Practical
Half-life
~30 min (short; cycled dosing typical)
Several hours
~2 hours
Varies by route
Administration
subq
subq
subq
subqim
Risk
Legal status
research only
research only
approved some regions
approved some regions
Safety
No major adverse events reported in available literature.
Limited human safety data; well tolerated anecdotally.
Very well tolerated. Mild injection-site reactions most common.
Injection can be uncomfortable (flushing, pressure). IV is well tolerated when titrated.
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