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| Attribute | Skin & Regeneration GHK-Cu | Anti-inflammatory KPV |
|---|---|---|
| Summary | The original copper peptide — collagen, skin tone, hair density. | Tiny tripeptide with outsized anti-inflammatory and gut-calming effects. |
| Mechanism | Copper-binding tripeptide. Stimulates collagen, elastin, and antioxidant gene expression; supports wound healing. | C-terminal fragment of alpha-MSH. Strong anti-inflammatory and mast-cell stabilizing effects. |
| Top outcomes |
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| Evidence | emerging | emerging |
| Half-life | Short systemically; topical action is local | Short |
| Administration | topical, subq | oral, subq, topical |
| Legal status | approved some regions | research only |
| Safety | Very well tolerated topically. Mild local reaction possible with injection. | Very well tolerated. |