/ database / Anti-inflammatory

KPV

Also: Lysine-Proline-Valine

Tiny tripeptide with outsized anti-inflammatory and gut-calming effects.

Evidence
emerging
Legal status
research only
Half-life
Short
Routes
oral · subq · topical
What it is

KPV is a three-amino-acid fragment of alpha-MSH with potent anti-inflammatory action, particularly in the gut and skin. Often stacked with BPC-157 for inflammatory bowel and skin conditions.

Mechanism

C-terminal fragment of alpha-MSH. Strong anti-inflammatory and mast-cell stabilizing effects.

Outcomes it's matched to
Safety

Very well tolerated.

  • Pregnancy
Legal context

Research-only.

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