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SemaglutideMOTS-c
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Overview
Summary
The category-defining GLP-1 for weight loss and metabolic health.
Mitochondrial peptide for metabolic flexibility and exercise capacity.
Category
GLP-1 Agonist
Mitochondrial
Mechanism
Long-acting GLP-1 receptor agonist. Slows gastric emptying, suppresses appetite, and improves glycemic control.
Mitochondrial-derived peptide. Activates AMPK, improves insulin sensitivity and mitochondrial function.
Effects
Top outcomes
- Fat loss94
- Inflammation50
- Energy80
- Longevity70
- Fat loss60
Evidence
Established
Emerging
Practical
Half-life
~7 days
Several hours
Administration
subqoral
subq
Risk
Legal status
rx only
research only
Safety
GI side effects (nausea, constipation) common. Lean-mass loss possible without resistance training.
Limited human safety data; well tolerated anecdotally.
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