/ database / Metabolic

AOD-9604

Also: Anti-Obesity Drug 9604 · GH fragment 176-191

GH-fragment with lipolytic action and no growth signaling.

Evidence
emerging
Legal status
research only
Half-life
Short
Routes
subq
What it is

AOD-9604 was originally developed as an obesity drug. It produces fat-loss-like effects of GH without engaging the IGF-1 axis. Clinical results in humans have been mixed.

Mechanism

Modified C-terminal fragment of GH. Promotes lipolysis without affecting IGF-1.

Outcomes it's matched to
Safety

Well tolerated in trials; efficacy modest.

  • Pregnancy
Legal context

Research-only; approved as food supplement in some jurisdictions.

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