Cagrilintide
Weekly amylin analog — complementary mechanism to GLP-1.
Evidence
emerging
Legal status
research only
Half-life
~7 days
Routes
subq
What it is
Cagrilintide is a long-acting analog of amylin, a pancreatic hormone co-secreted with insulin. It works through a different appetite pathway than GLP-1 and is the amylin half of CagriSema.
Mechanism
Long-acting amylin agonist that slows gastric emptying and increases satiety.
Outcomes it's matched to
- STRENGTH78%
Safety
Nausea on titration; generally well tolerated.
- Pregnancy
Legal context
Not approved. Investigational.