/ database / Antimicrobial Peptide

Human β-Defensin

Also: HBD-2

Endogenous antimicrobial peptide investigated for resistant infections.

Evidence
anecdotal
Legal status
research only
Half-life
Short
Routes
topical
What it is

Human β-defensins are part of the innate immune system. Synthetic analogs are being investigated for drug-resistant skin and respiratory infections.

Mechanism

Antimicrobial peptide active against bacteria, fungi and enveloped viruses; chemoattractant for immune cells.

Outcomes it's matched to
Safety

Limited data outside topical use.

Legal context

Research use only.

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